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Published on: March 14, 2019
Medication-related osteonecrosis of the jaws caused lethal sepsis in an edentulous patient with multiple systemic
Keisuke Yamashiro1, Aki Sato2, Fumihiko Okazaki2
1Department of Pathophysiology-Periodontal Science Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences 2-5-1 Shikata-cho Kita-ku Okayama 700-8525 Japan.
Abstract:
Medication-related osteonecrosis of the jaw (MRONJ) is developed even in the patients who are edentulous and treated with short-term bisphosphonate therapy and oral administration. It sometimes causes lethal sepsis in patients who have multiple health problems such as diabetes, cirrhosis, steroid use for interstitial pneumonia, sepsis, and spinal disk herniation.
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