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Updated: Mar 7, 2026

Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors
Published on: February 19, 2022
Severe upper gastrointestinal bleeding from gastrointestinal stromal tumor of the stomach
LaurenŢiu Augustus Barbu1, Nicolae Dragoş Mărgăritescu, Mirela Corina Ghiluşi
1Department of Surgery, University of Medicine and Pharmacy of Craiova, Romania; dmargaritescu@yahoo.com.
Abstract:
Gastrointestinal stromal tumor (GIST) is a mesenchymal tumor originating from the Cajal interstitial cells, immunologically characterized by the c-kit gene. The evolution may be asymptomatic, discovered by chance during a necropsy, upper gastrointestinal endoscopy or due to complications of type-algic, occlusive or hemorrhage. We present the case of a voluminous gastric GIST complicated with serious upper gastrointestinal bleeding in a patient with multiple hard associated diseases, undergoing an emergency surgery in hemorrhagic shock. The surgery consisted in the resection of the upper polar esogastric, the pathological and immunohistochemistry tests confirming the diagnosis of GIST. The evolution was unfavorable at discharge after 45 days after surgery by an anastomotic fistula.
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