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Related Concept Videos

Papillary Dermis01:11

Papillary Dermis

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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The papillary layer is made of loose, areolar connective tissue, which means the collagen...
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The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are  essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein...
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Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Reticular Dermis01:15

Reticular Dermis

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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
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Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Related Experiment Video

Updated: Mar 7, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Dermatoglyphics in Darier's Disease.

S Premalatha

    Indian Journal of Dermatology, Venereology and Leprology
    |February 9, 2017
    PubMed
    Summary

    Palmar dermatoglyphics in Darier's disease revealed distinct patterns, including a predominant whorl fingerprint pattern. These unique dermatoglyphic findings offer a valuable tool for studying this genetic skin condition.

    Area of Science:

    • Dermatology
    • Genetics
    • Dermatoglyphics

    Background:

    • Darier's disease is a rare genetic disorder affecting the skin.
    • Clinical diagnosis is typically confirmed by histopathology.
    • Palmar dermatoglyphics may offer insights into genetic skin conditions.

    Purpose of the Study:

    • To investigate characteristic palmar dermatoglyphic features in patients with Darier's disease.
    • To determine if dermatoglyphic patterns can serve as a diagnostic or research tool for Darier's disease.

    Main Methods:

    • Studied 9 cases of Darier's disease with confirmed clinical and histopathological diagnosis.
    • Utilized the Ink and Roller method for standard palmar dermatoglyphic analysis.
    • Compared dermatoglyphic findings in patients with control groups.

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    Main Results:

    • Predominant whorl pattern observed on fingertips in both sexes.
    • Identified characteristic features: Ridge Dissociation, wide flexion creases, white lines, and white dots.
    • Observed Sydney line and extra digital transverse crease; female fingertip patterns showed statistical significance compared to controls.

    Conclusions:

    • Significant dermatoglyphic findings suggest palmar analysis is a valuable tool for studying Darier's disease.
    • Dermatoglyphics, influenced by in utero genetic factors, can be applied to various genodermatoses.
    • Further application of dermatoglyphics in genodermatoses is warranted.