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Related Experiment Video

Updated: Mar 7, 2026

Generation of Human Motor Units with Functional Neuromuscular Junctions in Microfluidic Devices

Generation of Human Motor Units with Functional Neuromuscular Junctions in Microfluidic Devices

Published on: September 7, 2021

By Staying Together, Two Genes Keep the Motor Running.

Igor B Zhulin¹

¹Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; Department of Microbiology, University of Tennessee, Knoxville, TN 37996, USA.

Structure (London, England : 1993)

|February 9, 2017

Summary

Researchers found that two bacterial flagellar motor proteins interact, forming a shared structural domain. This discovery explains how their genes remain linked throughout evolution.

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Area of Science:

Structural biology
Microbiology
Evolutionary biology

Background:

The bacterial flagellar motor is a complex molecular machine essential for bacterial motility.
Understanding protein interactions within this motor is key to deciphering its function and evolution.

Purpose of the Study:

To investigate the structural basis of the interaction between two key proteins in the bacterial flagellar motor.
To elucidate the evolutionary implications of this protein interaction.

Main Methods:

The study utilized structural biology techniques (details not specified in the abstract).
Comparative analysis of protein structures and gene organization.

Main Results:

A shared structural domain was identified between two interacting proteins of the bacterial flagellar motor.
This shared domain facilitates a unique interaction mechanism.

Conclusions:

The interaction and shared domain between these flagellar motor proteins are evolutionarily conserved.
This structural arrangement likely plays a role in maintaining the co-evolution of the associated genes.