Hemodynamic Changes Following Routine Fluid Resuscitation in Patients With Blunt Trauma.

Area of Science:

• Emergency Medicine
• Critical Care
• Trauma Surgery

Background:

• Advanced Trauma Life Support (ATLS) is the standard for managing acute, life-threatening injuries.
• Trauma patient management presents significant challenges in resuscitation and fluid balance.

Purpose of the Study:

• To evaluate the impact of 1000 cc normal saline infusion on base excess (BE) and central venous pressure (CVP) in ICU trauma patients.
• To assess changes at one and six hours post-infusion.

Main Methods:

• Randomized selection of trauma patients admitted to the ICU with CVP line and hydration indication.
• Baseline measurements included BP, PR, RR, CVP, and blood gas analysis (Hb, pH, BE, PO2, HCO3, PCO2).
• Re-evaluation of parameters occurred one and six hours after 1000 cc normal saline injection.

Main Results:

• A statistically significant difference in base excess (BE) changes was observed based on hemoglobin (Hb) levels (P ≤ 0.05).
• No significant correlation was found between Injury Severity Score (ISS) and base excess (BE) changes (P ≥ 0.05).

Conclusions:

• One liter of normal saline statistically significantly decreased base deficit (BD) after one hour in trauma patients with moderate to severe ISS.
• Systolic blood pressure (SBP), pulse rate (PR), CVP, pH, HCO3, and Hb levels did not show statistically significant changes.