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Updated: Mar 7, 2026
05:44
Ultrasonographic Evaluation of Breast Cancer-related Lymphedema
Published on: January 12, 2017
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[Lymphoedema Following Regional Lymph Node Surgery for Breast Cancer].
Klinicka Onkologie : Casopis Ceske a Slovenske Onkologicke Spolecnosti
|February 11, 2017
Summary
Both axillary dissection and sentinel lymph node biopsy for breast cancer can cause lymphedema. While axillary dissection poses a higher risk, even sentinel lymph node biopsy carries a significant chance of developing this adverse effect.
Area of Science:
- Oncology
- Surgical Oncology
- Lymphedema Research
Background:
- Breast cancer treatment relies on multimodal approaches, including regional lymph node surgery.
- Axillary dissection (ALND) and sentinel lymph node biopsy (SLNB) are key surgical procedures.
- Both ALND and SLNB are associated with a risk of chronic lymphoedema, a significant adverse effect.
Purpose of the Study:
- To investigate the pathophysiology, predictive factors, and complications of lymphoedema after breast cancer surgery.
- To compare the incidence of lymphoedema following ALND versus SLNB.
- To review current trends aimed at reducing axillary surgery and explore lymphoedema management strategies.
Main Methods:
- Review of published studies comparing lymphoedema incidence after ALND and SLNB.
- Analysis of pathophysiology and predictive factors for lymphoedema.
- Examination of current trends in reducing axillary surgery radicality.
Main Results:
- Both ALND and SLNB carry a significant risk of lymphoedema, with ALND having a more severe impact.
- Medium-term lymphoedema incidence ranges from 7-59% after ALND and 0-14% after SLNB.
- The risk of lymphoedema after SLNB, despite being considered less invasive, is not negligible.
Conclusions:
- Clinically significant lymphoedema is a risk associated with both ALND and SLNB in breast cancer patients.
- Long-term monitoring of lymphoedema is crucial as survival rates increase.
- Research into less radical surgical techniques is supported to mitigate lymphoedema while maintaining treatment efficacy.
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