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Published on: August 15, 2025
Rare case of giant unicystic ameloblastoma: Luminal variant
Adarsh Kudva1, Abhay T Kamath1, Nirmala N Rao2
1a Department of Oral and Maxillofacial Surgery , Manipal College of Dental Sciences , Manipal , India.
Objective And Importance:
Ameloblastoma is a locally aggressive benign tumor, commonly occurring in the mandible. While giant ameloblastoma of multicystic or plexiform variant have been reported, the authors report a rare case of giant unicystic ameloblastoma of luminal variant, which was treated by compartmental resection and planned for delayed reconstruction.
Clinical Presentation:
A 46 year old male patient reported to the oral surgery out-patient department with a swelling of the left side mandible region of 2 years duration. He had undergone ayurvedic treatment for the same with no improvement. The size of the lesion on presenting was approximately 9 × 12 cm.
Intervention:
Compartmental resection with plan for secondary reconstruction, after adequate follow up period.
Conclusion:
While conservative management is being explored as a treatment option for unicystic ameloblastoma, resection is still the standard of care regardless of the histopathological subtype for giant lesions.

