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The application of a decision tree to establish the parameters associated with hypertension
Maryam Tayefi1, Habibollah Esmaeili2, Maryam Saberi Karimian3
1Biochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Insights
This study used a decision-tree algorithm to identify hypertension risk factors in over 9000 individuals. The model accurately identified key factors, aiding in developing hypertension management programs.
Area of Science:
- Cardiovascular Health
- Data Mining in Medicine
- Public Health Research
Background:
- Hypertension is a significant risk factor for cardiovascular disease (CVD).
- Identifying hypertension risk factors is crucial for effective management and prevention strategies.
- Data mining offers advanced methods for analyzing complex health datasets.
Purpose of the Study:
- To establish factors associated with hypertension using a decision-tree algorithm.
- To develop a predictive model for identifying individuals at risk of hypertension.
- To inform the development of targeted hypertension management programs.
Main Methods:
- A cross-sectional study involving 9078 subjects.
- A decision-tree algorithm was employed as a supervised classification method.
- Two models were evaluated using training (70%) and testing (30%) datasets, with ROC curve analysis for validation.
Main Results:
- The prevalence of hypertension in the study population was 32%.
- Decision-tree model I achieved 73% accuracy, 63% sensitivity, 77% specificity, and an AUC of 0.72.
- Decision-tree model II achieved 70% accuracy, 61% sensitivity, 74% specificity, and an AUC of 0.68.
Conclusions:
- A decision-tree model was successfully developed to identify hypertension risk factors.
- The model can be utilized for developing effective hypertension management strategies.
- This data mining approach provides valuable insights into hypertension etiology and prevention.
Introduction:
Hypertension is an important risk factor for cardiovascular disease (CVD). The goal of this study was to establish the factors associated with hypertension by using a decision-tree algorithm as a supervised classification method of data mining.
Methods:
Data from a cross-sectional study were used in this study. A total of 9078 subjects who met the inclusion criteria were recruited. 70% of these subjects (6358 cases) were randomly allocated to the training dataset for the constructing of the decision-tree. The remaining 30% (2720 cases) were used as the testing dataset to evaluate the performance of decision-tree. Two models were evaluated in this study. In model I, age, gender, body mass index, marital status, level of education, occupation status, depression and anxiety status, physical activity level, smoking status, LDL, TG, TC, FBG, uric acid and hs-CRP were considered as input variables and in model II, age, gender, WBC, RBC, HGB, HCT MCV, MCH, PLT, RDW and PDW were considered as input variables. The validation of the model was assessed by constructing a receiver operating characteristic (ROC) curve.
Results:
The prevalence rates of hypertension were 32% in our population. For the decision-tree model I, the accuracy, sensitivity, specificity and area under the ROC curve (AUC) value for identifying the related risk factors of hypertension were 73%, 63%, 77% and 0.72, respectively. The corresponding values for model II were 70%, 61%, 74% and 0.68, respectively.
Conclusion:
We have developed a decision tree model to identify the risk factors associated with hypertension that maybe used to develop programs for hypertension management.
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