Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fates of Pyruvate01:20

Fates of Pyruvate

10.3K
Pyruvate is the end product of glycolysis, where glucose is oxidized to pyruvate, simultaneously reducing NAD+ to NADH. Two molecules of ATP are also produced by substrate-level phosphorylation.
In aerobic organisms, pyruvate is metabolized via the citric acid cycle to produce reduced coenzymes NADH and FADH2. These coenzymes are then oxidized in the electron transport chain to produce ATP and, in the process, regenerate the NAD+ and FAD. As seen in some cell types and organisms, fermentation...
10.3K
Hydroboration-Oxidation of Alkenes03:08

Hydroboration-Oxidation of Alkenes

10.9K
In addition to the oxymercuration–demercuration method, which converts the alkenes to alcohols with Markovnikov orientation, a complementary hydroboration-oxidation method yields the anti-Markovnikov product. The hydroboration reaction, discovered in 1959 by H.C. Brown, involves the addition of a B–H bond of borane to an alkene giving an organoborane intermediate. The oxidation of this intermediate with basic hydrogen peroxide forms an alcohol.
10.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

BMI-based metabolic syndrome Z-score and gastrointestinal cancers: A cohort study.

Medicine·2026
Same author

Dietary inflammatory index and lung cancer risk: multi-cohort evidence and plasma proteomic profiles.

Lung cancer (Amsterdam, Netherlands)·2026
Same author

Long-term cardiovascular risk in survivors of hematologic malignancies: a meta-analysis.

BMC cancer·2026
Same author

Spirocyclization-Enabled Remote Phosphorothiolation of Nonactivated Arenes via Dual Photoredox/Copper-Catalyzed Dearomatization.

Organic letters·2026
Same author

Butyric acid production from corn: economics of fermentative production of a novel biobased chemical.

Journal of industrial microbiology & biotechnology·2026
Same author

In-situ surface-enhanced Raman spectroscopy monitoring of rhodamine 6G degradation in agricultural products by TiO<sub>2</sub>@COF@Au multifunctional photocatalyst.

Talanta·2026
Same journal

Antifungal activity of rhein against Candida albicans with insights into its mechanism of action.

World journal of microbiology & biotechnology·2026
Same journal

The calcium signal regulatory network and the roles of calcium-binding proteins in bacteria.

World journal of microbiology & biotechnology·2026
Same journal

Effects of temperature and relative humidity on germination, vegetative growth, sporulation, and pathogenicity of native Beauveria bassiana isolates and formulations against adult desert locust (Schistocerca gregaria ForskĂĄl).

World journal of microbiology & biotechnology·2026
Same journal

Mirubactin-like siderophore-Fe complex from Amycolatopsis lurida strain 407 is associated with improved plant Fe status and yield in chickpea (Cicer arietinum L.) under in vitro conditions.

World journal of microbiology & biotechnology·2026
Same journal

A non‑natural shortcut biosynthetic route enables de novo microbial production of 3‑hydroxyanthranilic and quinolinic acids.

World journal of microbiology & biotechnology·2026
Same journal

Anti-bacterial effects of gallic acid-loaded graphene oxide nanocomposite (GAGO) against Vibrio spp., its potential mechanism of action and toxicity against Artemia nauplii.

World journal of microbiology & biotechnology·2026
See all related articles

Related Experiment Video

Updated: Jan 6, 2026

Ammonia Fiber Expansion AFEX Pretreatment of Lignocellulosic Biomass
09:30

Ammonia Fiber Expansion AFEX Pretreatment of Lignocellulosic Biomass

Published on: April 18, 2020

14.3K

Progress and perspectives on improving butanol tolerance.

Siqing Liu1, Nasib Qureshi2, Stephen R Hughes3

  • 1Renewable Product Technology Research Unit, National Center for Agricultural Utilization Research, Agricultural Research Service, United States Department of Agriculture, 1815 N. University St., Peoria, IL, 61604, USA. Siqing.liu@ars.usda.gov.

World Journal of Microbiology & Biotechnology
|February 13, 2017
PubMed
Summary
This summary is machine-generated.

Butanol fermentation for biofuels faces toxicity challenges. This review explores microbial responses to butanol stress and genetic strategies to enhance biofuel production and tolerance in key industrial microorganisms.

Keywords:
ButanolFermentationStrain developmentTolerance

More Related Videos

Production of Chemicals by Klebsiella pneumoniae Using Bamboo Hydrolysate as Feedstock
07:24

Production of Chemicals by Klebsiella pneumoniae Using Bamboo Hydrolysate as Feedstock

Published on: June 29, 2017

9.4K
Techniques for the Evolution of Robust Pentose-fermenting Yeast for Bioconversion of Lignocellulose to Ethanol
14:53

Techniques for the Evolution of Robust Pentose-fermenting Yeast for Bioconversion of Lignocellulose to Ethanol

Published on: October 24, 2016

11.7K

Related Experiment Videos

Last Updated: Jan 6, 2026

Ammonia Fiber Expansion AFEX Pretreatment of Lignocellulosic Biomass
09:30

Ammonia Fiber Expansion AFEX Pretreatment of Lignocellulosic Biomass

Published on: April 18, 2020

14.3K
Production of Chemicals by Klebsiella pneumoniae Using Bamboo Hydrolysate as Feedstock
07:24

Production of Chemicals by Klebsiella pneumoniae Using Bamboo Hydrolysate as Feedstock

Published on: June 29, 2017

9.4K
Techniques for the Evolution of Robust Pentose-fermenting Yeast for Bioconversion of Lignocellulose to Ethanol
14:53

Techniques for the Evolution of Robust Pentose-fermenting Yeast for Bioconversion of Lignocellulose to Ethanol

Published on: October 24, 2016

11.7K

Area of Science:

  • Biotechnology and Biofuels
  • Microbial Physiology
  • Synthetic Biology

Background:

  • Butanol fermentation is a promising renewable technology for biofuels and chemical feedstocks.
  • Microbial toxicity to butanol hinders cost-effective production and recovery.
  • Developing butanol-tolerant strains is crucial for advancing this technology.

Purpose of the Study:

  • To review microbial responses to high butanol concentrations.
  • To explore genetic engineering strategies for improved butanol tolerance and production.
  • To identify key genes and physiological mechanisms conferring butanol resistance.

Main Methods:

  • Literature review of studies on butanol tolerance in various microorganisms.
  • Analysis of inherent microbial responses to butanol stress.
  • Examination of genetic engineering approaches to enhance butanol production.

Main Results:

  • Different microorganisms exhibit varied inherent tolerance mechanisms to butanol.
  • Genetic engineering efforts have shown promise in improving butanol tolerance in several strains.
  • Understanding butanol resistance physiology is key to strain development.

Conclusions:

  • Enhanced microbial butanol tolerance is achievable through understanding inherent responses and targeted genetic engineering.
  • This review consolidates knowledge to guide future strain development for efficient butanol fermentation.
  • Identifying specific butanol tolerance genes will accelerate the development of superior microbial cell factories.