Low PAPP-A: what are the clinical implications?

Harmonie Lau1, Chaminda Amarasekara1, Talat Uppal1

  • 1Northern Beaches Maternity Manly Hospital Manly New South Wales 2095 Australia.

Ultrasound and pulsed Doppler can assist in confirming impaired placentation looking at fetal biometry and umbilical artery Dopplers. The authors recommend confirmation of fetal wellbeing at 28-30 weeks with a PAPP-A level below the first centile.

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