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Transdermal Spirit (Methanol) Poisoning: A Case Report
Hatice Dogan1, Banu Yilmaz Karakus1, Kubra Serefoglu Cabuk2
1Department of Emergency Medicine, Bagcilar Research and Training Hospital, Istanbul, Turkey.
Iranian Red Crescent Medical Journal
|February 14, 2017
Summary
Transdermal methanol poisoning is a rare but serious condition. This case highlights the importance of considering methanol toxicity even when symptoms are unusual, like knee pain and redness after topical application.
Area of Science:
- Toxicology
- Emergency Medicine
- Dermatology
Background:
- Methanol is a potent toxin causing severe health issues through oral, inhalation, or dermal exposure.
- Transdermal methanol poisoning is infrequently documented but can lead to significant complications.
- Early recognition and intervention are crucial for managing methanol toxicity.
Observation:
- A 59-year-old male presented with blurred vision and knee pain after applying alcohol-soaked cotton to his knees for 10 hours.
- Physical examination revealed only erythema on the knees; funduscopic examination showed no signs of poisoning.
- Arterial blood gas analysis indicated a high anion gap metabolic acidosis.
Findings:
- The patient was diagnosed with methanol poisoning secondary to transdermal absorption.
- Hemodialysis was initiated to correct the severe metabolic acidosis.
- The patient recovered and was discharged from the Intensive Care Unit without any lasting effects.
Implications:
- This case underscores the potential for severe methanol poisoning via transdermal routes, which may be overlooked.
- Clinicians should maintain a high index of suspicion for methanol toxicity in patients with unexplained metabolic acidosis, regardless of exposure history.
- Raising awareness of transdermal methanol poisoning is vital, particularly in regions where such exposures might be more common.