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Updated: Mar 7, 2026

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Published on: August 12, 2020
Common Skin Conditions in Children: Neonatal Skin Lesions
Brian Z Rayala1, Dean S Morrell2
1University of North Carolina Chapel Hill School of Medicine Department of Family Medicine, 590 Manning Drive, Chapel Hill, NC 27599.
Insights
Most newborns have common skin findings, often benign and self-resolving. Differentiating these from serious infections or inflammatory conditions is crucial for appropriate newborn skin care.
Area of Science:
- Neonatal dermatology
- Pediatric skin conditions
Background:
- Over 95% of newborns exhibit cutaneous findings, frequently causing parental concern.
- Many common neonatal skin conditions are benign and self-limiting, such as milia and erythema toxicum neonatorum.
- Accurate differentiation from serious infectious or inflammatory dermatoses is essential.
Purpose of the Study:
- To review common benign neonatal skin findings.
- To highlight the importance of distinguishing benign conditions from severe ones.
- To provide guidance on newborn skin care.
Main Methods:
- Literature review of neonatal skin conditions.
- Discussion of differential diagnoses for pustular eruptions.
- Overview of recommended newborn skin care practices.
Main Results:
- Common benign findings include milia, cutis marmorata, congenital dermal melanocytosis, and benign neonatal pustular eruptions.
- Serious conditions to differentiate include bacterial (e.g., bullous impetigo), viral (e.g., neonatal herpes), and fungal (e.g., candidiasis) infections, as well as Langerhans cell histiocytosis.
- Seborrheic dermatitis and diaper dermatitis represent common diagnoses with varied etiologies.
Conclusions:
- Recognizing benign neonatal skin conditions is key for reducing parental anxiety.
- Distinguishing benign from severe dermatoses ensures timely and appropriate management.
- Essential newborn skin care includes bathing, umbilical cord care, and emollient use to support skin barrier function.
Abstract:
Skin findings during the initial month of life are ubiquitous. One study estimated that more than 95% of newborns have cutaneous findings, which often are distressing to parents but frequently are benign and self-limited. Among them are milia, cutis marmorata, congenital dermal melanocytosis, and the benign neonatal pustular eruptions (eg, benign cephalic pustulosis, erythema toxicum neonatorum, transient neonatal pustular melanosis). Clinicians need to recognize these benign skin conditions and differentiate them from more serious conditions, such as infectious pustular eruptions from bacterial, viral, and fungal causes, and inflammatory conditions, such as Langerhans cell histiocytosis. Notable bacterial pustular eruptions are bullous impetigo and congenital syphilis. Viral pustular dermatoses include neonatal herpes simplex virus infection and varicella zoster virus infection, which consists of congenital varicella syndrome, perinatal varicella, and infantile zoster. Fungal pustular eruptions include congenital and neonatal candidiasis. Seborrheic dermatitis is a self-limited condition that occurs with varying severity; symptomatic treatment is reserved for the more severe forms. Diaper dermatitis encompasses a broad clinical diagnosis, including allergic and irritant contact dermatitis, atopic dermatitis, infections, psoriasis, and other dermatologic conditions. Critical components of newborn skin care are immersion bathing, umbilical cord care, and use of emollients to augment skin barrier function.
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