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A Double Humanized BLT-mice Model Featuring a Stable Human-Like Gut Microbiome and Human Immune System
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Enhancing the clinical coverage and anticancer efficacy of immune checkpoint blockade through manipulation of the gut

Jonathan M Pitt1, Marie Vétizou1, Ivo Gomperts Boneca2

  • 1Institut de Cancérologie Gustave Roussy Cancer Campus (GRCC), Villejuif, France; INSERM Unit U1015, Villejuif, France; Faculté de Médecine, Université Paris Sud, Université Paris-Saclay, Le Kremlin Bicêtre, France.

Oncoimmunology
|February 16, 2017
PubMed

Keywords:
Anti-CTLA-4BacteroidesT cellcanceripilimumabmicrobiomemicrobiota

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