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Updated: Mar 7, 2026

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
Published on: July 4, 2007
Relapsing polychondritis with meningoencephalitis
Monica Tsai1, Mengjun Hu2, Jamie Zussman3
1Department of Internal Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Abstract:
Relapsing polychondritis (RP) is a rare autoimmune disease of the cartilaginous structures of the body with many systemic manifestations including meningoencephalitis (ME). We present a case of a man with RP-associated ME that was responsive to steroid treatment. An updated literature review of 7 cases of RP-associated ME also is provided. Early diagnosis of this condition may be of benefit to this select population of patients, and further research regarding the prognosis, mechanisms, and treatment of RP may be necessary in the future.
Insights
Relapsing polychondritis (RP) with meningoencephalitis (ME) is rare. Steroid treatment showed positive results in a patient with RP-associated ME, suggesting potential benefits for early diagnosis and further research.
Area of Science:
- Rheumatology
- Neurology
- Autoimmune Diseases
Background:
- Relapsing polychondritis (RP) is a rare systemic autoimmune disease affecting cartilaginous structures.
- Meningoencephalitis (ME) is a rare but serious systemic manifestation of RP.
- RP-associated ME presents diagnostic and therapeutic challenges.
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