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Space-maintaining management in maxillary sinus lifting: a novel technique using a resorbable polymeric
G Cossellu1, G Farronato1, D Farronato2
1Department of Biomedical, Surgical and Dental Sciences, University of Milan, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
International Journal of Oral and Maxillofacial Surgery
|February 18, 2017
Summary
This study explored a novel non-graft sinus lifting technique using a space-maintaining gel, demonstrating significant new bone formation. The procedure shows promise for promoting bone regeneration in the maxillary sinus.
Area of Science:
- Oral and Maxillofacial Surgery
- Biomaterials Science
- Regenerative Medicine
Background:
- Sinus floor elevation is crucial for dental implant placement in the atrophic posterior maxilla.
- Traditional methods involve grafting materials, acting as scaffolds for new bone formation.
- Alternative techniques are sought to simplify procedures and enhance bone regeneration.
Purpose of the Study:
- To evaluate a non-graft sinus lifting procedure utilizing a resorbable polymeric thermo-reversible gel.
- To assess the efficacy of this space-maintaining gel in promoting new bone formation within the maxillary sinus.
- To histologically and histomorphometrically analyze bone regeneration and tissue response.
Main Methods:
- A space-maintaining sinus lifting technique with a resorbable gel was performed on 11 patients.
- A 6-month healing period preceded implant placement and biopsy.
- Histological and histomorphometric analyses evaluated new bone, residual gel, and fibrous tissue percentages.
Main Results:
- Histological examination revealed new bone formation with minimal fibrous tissue and no severe inflammation.
- Newly formed bone constituted 54-60% of the analyzed area, comprising lamellar and woven bone.
- Minimal residual gel and connective tissue were observed, with no foreign-body reaction.
Conclusions:
- The non-graft sinus lifting procedure using a space-maintaining gel effectively stimulates predictable bone formation.
- This technique represents a viable alternative for promoting bone regeneration in the maxillary sinus.
- The resorbable gel serves as a scaffold, facilitating bone development without adverse tissue reactions.

