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The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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The muscles of the forearm that move the wrist, hand, and digits are numerous and diverse. They can be classified into two groups based on their location and function — the anterior and posterior compartment muscles.
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Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
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Reticular Dermis01:15

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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
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The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are  essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein...
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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
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Plamar Dermatoglyphics in Psorlasis-a Pilot Study.

K S Nagar, N N Laha, C N Sethi

    Indian Journal of Dermatology, Venereology and Leprology
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    Summary
    This summary is machine-generated.

    Palmar dermatoglyphics, the study of fingerprint patterns, revealed significant differences in certain ridge counts and palm measurements between female psoriasis patients and healthy individuals. These findings suggest potential links between dermatoglyphic features and psoriasis susceptibility.

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    Area of Science:

    • Dermatology
    • Human Genetics
    • Anthropometry

    Background:

    • Psoriasis is a chronic inflammatory skin condition with a complex etiology.
    • Dermatoglyphics, the study of skin patterns on fingers and palms, has been explored for associations with various diseases.
    • Limited research exists on palmar dermatoglyphic variations in female psoriasis patients.

    Purpose of the Study:

    • To investigate differences in palmar dermatoglyphic parameters between female patients with psoriasis and healthy controls.
    • To identify specific dermatoglyphic features that may be associated with psoriasis.

    Main Methods:

    • A case-control study comparing 24 female psoriasis patients and 25 healthy females.
    • Analysis of two main dermatoglyphic parameters: ridge counts and palmar metric analyses.
    • Statistical comparison of mean values for selected parameters between the two groups.

    Main Results:

    • Statistically significant differences were observed in mean ridge counts between psoriasis patients and controls in the right palm digit I and left palm digit IV.
    • Metric analysis revealed a statistically significant difference in the mean vertical distance from the a-d ridge count to the axial triradius on the left side.

    Conclusions:

    • Palmar dermatoglyphic patterns, specifically certain ridge counts and palmar measurements, differ significantly between female psoriasis patients and normal individuals.
    • These dermatoglyphic variations may serve as potential indicators or contribute to understanding the pathogenesis of psoriasis.