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Visualizing BPA by molecularly imprinted ratiometric fluorescence sensor based on dual emission nanoparticles
1School of Chemistry and Chemical Engineering, Linyi University, Linyi 276005, China.
Biosensors & Bioelectronics
|February 19, 2017
Summary
A new dual emission nanoparticle sensor simplifies detecting Bisphenol A (BPA). This highly sensitive method offers a convenient and reliable way to identify BPA in real-world samples like water and food.
Area of Science:
- Nanotechnology
- Analytical Chemistry
- Biomedical Engineering
Background:
- Ratiometric fluorescent probes often require complex synthesis.
- Dual emission fluorescent nanoparticles offer a simpler construction approach.
Purpose of the Study:
- To develop a facile strategy for a ratiometric fluorescence molecularly imprinted sensor.
- To detect Bisphenol A (BPA) using dual emission nanoparticles (d-NPs).
Main Methods:
- Prepared d-NPs comprising carbon dots and gold nanoclusters via a seed growth co-microwave method.
- Utilized d-NPs for a ratiometric fluorescence molecularly imprinted sensor.
- Employed dual emission at 460nm and 580nm for BPA detection.
Main Results:
- Achieved a simplified sensor preparation process.
- Improved sensitivity with a detection limit of 29nM for BPA.
- Demonstrated feasible visualization of BPA via distinct fluorescence color changes.
- Validated the method in real samples (water, canned food, feeding bottles) with high recovery rates (95.9-98.9% and 92.6-98.6%).
Conclusions:
- The developed d-NPs based ratiometric fluorescence sensor is convenient, reliable, and practical.
- Offers a highly sensitive and selective method for BPA detection.
- Shows excellent performance in real sample analysis, aligning with accredited methods.
