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[Adherence in specific immunotherapy].

M-L Lemberg¹, M-J Joisten¹, R Mösges²

¹Institut für Medizinische Statistik, Informatik und Epidemiologie, Medizinische Fakultät, Universität zu Köln, Lindenburger Allee 42, 50931, Köln, Deutschland.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete

|February 19, 2017

Summary

This summary is machine-generated.

Specific immunotherapy (SIT) for allergies shows poor patient adherence, with many discontinuing treatment early. Improving adherence requires addressing complex factors like the physician-patient relationship and patient understanding.

Keywords:

Allergies Compliance Persistence Subcutaneous Sublingual

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Area of Science:

Allergy and Immunology
Clinical Medicine

Background:

Allergies are a growing public health concern in Western countries.
Specific immunotherapy (SIT) is a causal treatment for allergies, aiming for symptom relief or cure.
Patient adherence to SIT is a significant challenge, impacting treatment effectiveness.

Purpose of the Study:

To highlight the problem of poor patient adherence in sublingual immunotherapy (SLIT) and subcutaneous immunotherapy (SCIT).
To discuss the complex, interdependent factors influencing patient adherence to allergy immunotherapy.
To emphasize the critical role of the physician-patient relationship and patient comprehension in successful SIT.

Main Methods:

Review of existing literature on patient adherence rates in SLIT and SCIT.
Analysis of factors contributing to premature discontinuation of SIT.
Exploration of the multifaceted nature of patient adherence in allergy treatment.

Main Results:

High rates of incomplete SIT treatment are reported, with 41-93% for SLIT and 40-77% for SCIT in 3-year studies.
Patient adherence is influenced by a complex interplay of various factors.
Physician-patient relationship and patient understanding of allergy and treatment are key determinants of success.

Conclusions:

Poor adherence significantly compromises the efficacy of specific immunotherapy for allergies.
Addressing patient adherence requires a comprehensive approach, considering patient education and strengthening the physician-patient alliance.
Future strategies should focus on improving patient persistence to maximize the benefits of SIT.