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Related Concept Videos

Epilepsy and Seizures: Overview01:24

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Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
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Antiepileptic Drugs: Glutamate Antagonists01:14

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Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...
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Antiepileptic Drugs: Sodium Channel Blockers01:08

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Antiepileptic drugs are specialized medications that prevent seizures in individuals diagnosed with epilepsy. These drugs primarily function by blocking the movement of sodium ions through channels in the neuronal membrane, inhibiting the repetitive firing of action potentials often associated with seizures.
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Electroconvulsive Therapy01:30

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Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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Antiepileptic Drugs: Potassium Channel Activators01:20

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Ezocgabine or retigabine, an antiepileptic drug of remarkable efficacy, has revolutionized the management of seizures. It is a potassium channel activator, explicitly targeting the family of Q subtype potassium channels. It enhances the transmembrane potassium currents, regulating neuronal excitability. This action stabilizes the resting membrane potential, a pivotal factor in mitigating the hyperexcitability that characterizes epilepsy.
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Nursing management of dysrhythmias involves the following:AssessmentSubjective Assessment:The initial step involves gathering patient-reported symptoms such as dizziness, palpitations, and chest discomfort. It is crucial to collect a detailed history, including previous heart conditions, current medication use, and lifestyle factors like caffeine and alcohol consumption.Objective Assessment:This involves observing clinical signs such as jugular venous distention, cool and pale skin, and...
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Related Experiment Video

Updated: Mar 7, 2026

Manipulation of Epileptiform Electrocorticograms ECoGs and Sleep in Rats and Mice by Acupuncture
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The Managing Epilepsy Well Network:: Advancing Epilepsy Self-Management.

Martha Sajatovic1, Barbara C Jobst2, Ross Shegog3

  • 1Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, Ohio.

American Journal of Preventive Medicine
|February 21, 2017
PubMed
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The Managing Epilepsy Well (MEW) Network advances epilepsy self-management through scalable, evidence-based programs. This research network utilizes e-health strategies to improve care accessibility and reduce the burden of epilepsy.

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Area of Science:

  • Public Health
  • Chronic Disease Management
  • Epilepsy Research

Background:

  • Epilepsy affects 2.9 million Americans, presenting challenges in management, treatment, and social well-being.
  • Previous reports highlighted knowledge gaps and the need for scalable epilepsy self-management programs.
  • The Centers for Disease Control and Prevention established the Managing Epilepsy Well (MEW) Network to address these needs.

Discussion:

  • The MEW Network focuses on developing and disseminating effective epilepsy self-management interventions.
  • Interventions utilize e-health strategies to overcome barriers like transportation, functional limitations, and stigma.
  • Key strengths include collaboration, community partnerships, e-health, and a diverse prevention portfolio.

Key Insights:

  • The MEW Network's research pipeline covers efficacy, effectiveness, and dissemination of epilepsy self-management tools.
  • The network has produced significant scholarly output, including journal articles, reports, book chapters, and presentations.
  • Two MEW programs have been successfully adopted and disseminated by national and affiliate Epilepsy Foundations.

Outlook:

  • Expansion of MEW Network membership aims to broaden reach and public health impact.
  • Continued focus on evidence-based, scalable interventions and e-health strategies is crucial.
  • Sustained partnerships and knowledge translation will enhance the long-term sustainability of MEW programs.