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Haematogenous candida endophthalmitis after abdominal surgery
1Department of Ophthalmology, University Central Hospital, Turku, Finland.
Acta Ophthalmologica
|August 1, 1987
Summary
Bilateral endogenous fungal endophthalmitis after surgery can lead to vision loss. Prompt treatment with antifungals and corticosteroids may improve outcomes, but complications like scarring can impair vision.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Mycology
Background:
- Endogenous fungal endophthalmitis is a rare but serious intraocular infection.
- Abdominal surgery is a potential risk factor for developing endogenous fungal infections.
Observation:
- Two cases of bilateral endogenous Candida endophthalmitis following abdominal surgery are presented.
- Case 1: Treated with amphotericin B and ketoconazole, with resolution of lesions but subsequent subretinal neovascularization and macular hole.
- Case 2: Treated with oral corticosteroids for active lesions, resulting in resolution of lesions and vitreous opacities without scarring, with partial visual recovery.
Findings:
- Antifungal therapy (amphotericin B, ketoconazole) can resolve active chorioretinal lesions in Candida endophthalmitis.
- Corticosteroids may help manage inflammatory responses in fungal endophthalmitis.
- Complications such as subretinal neovascularization and macular holes can occur despite treatment, leading to permanent visual impairment.
Implications:
- Early diagnosis and aggressive treatment are crucial for managing endogenous fungal endophthalmitis.
- Ophthalmologists should consider fungal endophthalmitis in patients with risk factors like recent surgery.
- Long-term visual outcomes depend on the extent of infection and development of complications.