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Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons

Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons

Published on: August 23, 2016

Zika virus: An overview.

Gautam Rawal¹, Sankalp Yadav², Raj Kumar¹

¹Department of Respiratory Intensive Care, Max Super Specialty Hospital, Saket, New Delhi, India.

Journal of Family Medicine and Primary Care

|February 21, 2017

Summary

This summary is machine-generated.

The Zika virus outbreak, declared a global health emergency, is linked to severe infant deformities like microcephaly. This review covers Zika virus diagnosis, features, and management, highlighting its threat to India.

Keywords:

Aedes Flavivirus Zika arbovirus microcephaly virus

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Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult

Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult

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Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult

Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult

Published on: April 26, 2018

Area of Science:

Virology
Public Health
Infectious Diseases

Background:

The Zika virus outbreak, originating in Southern America in December 2015, rapidly escalated into a global health concern.
The World Health Organization declared a public health emergency in February 2016 due to Zika's association with congenital abnormalities, notably microcephaly in infants.
The virus's swift transmission across the Americas and into Asia, with proximity to India, poses a significant public health threat.

Purpose of the Study:

To provide a comprehensive overview of the Zika virus.
To detail the diagnostic methods for Zika virus infection.
To outline the clinical manifestations and management strategies for Zika virus.

Main Methods:

This article is a review based on existing literature and public health reports.
Information was gathered on the epidemiology, clinical presentation, and diagnostic approaches for Zika virus.
Management guidelines and public health recommendations were synthesized.

Main Results:

Zika virus is primarily transmitted by Aedes mosquitoes and is associated with significant neurological and congenital complications.
Diagnosis involves laboratory testing, including PCR and serology.
Clinical management focuses on supportive care and monitoring for complications.

Conclusions:

Understanding Zika virus's transmission, diagnosis, and clinical impact is crucial for effective public health response.
The potential threat to regions like India necessitates preparedness and awareness.
Continued research and surveillance are essential for managing Zika virus and its associated risks.