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Remote Limb Ischemic Preconditioning: A Neuroprotective Technique in Rodents
Published on: June 2, 2015
Dexmedetomidine-induced neuroprotection: is it translational?
Yunzhen Wang1, Ruquan Han2, Zhiyi Zuo3
1Department of Anesthesiology, University of Virginia, Charlottesville, Virginia 22901, USA; Department of Anesthesiology, Beijing Tian Tan Hospital, Capital Medical University, Beijing 100050, China.
Abstract:
Dexmedetomidine is often used in anesthesia and critical care medicine practice to sedate patients. Its neuroprotective effects have been shown in various ischemic and hemorrhagic brain injury models of animals. Randomized clinical trials have indicated that dexmedetomidine can improve outcome of patients under intensive care. Clinical trials are needed to determine whether dexmedetomidine can provide neuroprotection against ischemic and hemorrhagic stroke.
