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Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

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Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
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Pathophysiology of Diabetes01:20

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
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Diabetes Mellitus: Overview and Type I Subtype01:22

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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Skin Diseases and Disorders01:23

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Related Experiment Video

Updated: Mar 7, 2026

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
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Psoriasis and Diabetes Millitus.

J A Sundharam, Ratan Singh, P S Agarwal

    Indian Journal of Dermatology, Venereology and Leprology
    |February 21, 2017
    PubMed
    Summary

    Psoriasis patients show a higher incidence of abnormal glucose tolerance compared to healthy individuals. This suggests a potential link between psoriasis severity and impaired glucose metabolism.

    Area of Science:

    • Dermatology
    • Endocrinology
    • Metabolic Disorders

    Background:

    • Psoriasis is a chronic inflammatory skin condition.
    • Metabolic abnormalities are increasingly recognized in various chronic diseases.

    Purpose of the Study:

    • To investigate glucose tolerance in patients with uncomplicated psoriasis.
    • To explore the relationship between psoriasis severity and glucose metabolism.

    Main Methods:

    • Oral and steroid-primed glucose tolerance tests were administered.
    • Twenty patients with uncomplicated psoriasis and twenty matched controls were included.

    Main Results:

    • 30% of psoriasis patients exhibited abnormal glucose tolerance, compared to 5% in controls (p < 0.05).

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  • A correlation was observed between the extent of skin surface area affected by psoriasis and abnormal glucose tolerance.
  • Conclusions:

    • Patients with psoriasis have a significantly higher prevalence of abnormal glucose tolerance.
    • The severity of psoriasis may be associated with metabolic dysfunction, specifically impaired glucose regulation.