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Dynamic contrast-enhanced endoscopic ultrasound: A quantification method.

Christoph F Dietrich1, Yi Dong1, Eckhart Froehlich2

  • 1Department of Internal Medicine 2, Caritas-Krankenhaus Bad Mergentheim, Academic Teaching Hospital of the University of Wurzburg, Germany.

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Summary
This summary is machine-generated.

Dynamic contrast-enhanced ultrasound (DCE-US) is standardized, but contrast-enhanced endoscopic ultrasound (CE-EUS) use is less understood. This review covers clinical applications for both, highlighting DCE-US for predicting tumor response to anti-angiogenesis drugs.

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Area of Science:

  • Medical imaging
  • Oncology
  • Gastroenterology

Background:

  • Dynamic contrast-enhanced ultrasound (DCE-US) guidelines are established, with a European position paper detailing its applications.
  • Contrast-enhanced endoscopic ultrasound (CE-EUS) applications are less defined compared to DCE-US.
  • There is a need to review and consolidate the clinical utility of both DCE-US and CE-EUS.

Purpose of the Study:

  • To review and discuss the current clinical applications of contrast-enhanced endoscopic ultrasound (CE-EUS).
  • To review and discuss the current clinical applications of dynamic contrast-enhanced ultrasound (DCE-US).
  • To compare the established and emerging uses of these advanced ultrasound techniques.

Main Methods:

  • Literature review and discussion of existing clinical data and guidelines.
  • Synthesis of information regarding the standardization and application of DCE-US.
  • Exploration of the emerging clinical roles and evidence for CE-EUS.

Main Results:

  • DCE-US is a validated tool, particularly for predicting tumor response to anti-angiogenesis therapies.
  • The clinical utility of CE-EUS is still under active investigation and development.
  • Both techniques offer valuable insights into tissue vascularity and perfusion.

Conclusions:

  • DCE-US plays a significant role in oncological treatment monitoring.
  • CE-EUS holds potential for various gastrointestinal and other applications, requiring further research.
  • Standardization and broader adoption of CE-EUS may follow as evidence accumulates.