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Atrial angioleiomyoma with myopericytoma-like features: a case report
Hussein Nassereddine1, Aurélie Cazes2, Constance Verdonk3
1AP-HP, Bichat-Hospital, Department of Pathology, Paris Descartes University, Paris, France.
Insights
A rare angioleiomyoma (ALM) was surgically resected from the right atrium. This benign tumor, typically found elsewhere, can mimic cardiac myxoma.
Area of Science:
- Cardiovascular Pathology
- Surgical Oncology
Background:
- A 66-year-old female presented with a right atrial mass.
- History of cerebrovascular accident secondary to carotid artery stenosis.
Observation:
- Transthoracic and transesophageal echocardiography identified a 3.4-cm right atrial mass.
- Surgical resection of the mass located in the interatrial septum.
Findings:
- Microscopic evaluation confirmed the mass as an angioleiomyoma (ALM).
- Histological features distinct from atrial myxoma.
Implications:
- Angioleiomyoma, though common in other locations, is a novel finding in the atrium.
- ALM should be included in the differential diagnosis for atrial tumors, alongside cardiac myxoma.
Abstract:
A 66-year-old female patient was referred to our hospital for resection of a right atrial mass. Four months earlier, she had suffered an acute cerebrovascular accident due to occlusion of the sylvian segment of the right middle cerebral artery from atheromatous tight stenosis in the right internal carotid artery. Later, investigations with transthoracic and transesophageal echocardiography revealed a 3.4-cm right atrial mass that was resected surgically. Microscopic evaluation revealed a well-circumscribed nodular tumor, located within the interatrial septum, and corresponding to an angioleiomyoma (ALM). This tumor differs histologically from atrial myxoma. ALM is a ubiquitous benign tumor but has never been reported to occur in the atrium. ALM can mimic cardiac myxoma and should be considered in the differential diagnosis of atrial tumors.
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