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Updated: Mar 7, 2026

Quantification of Diabetes-induced Adherent Leukocytes in Retinal Vasculature
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Published on: January 24, 2025

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Bullosis Diabeticorum.

K C Mohanty, Ratan Singh, B Lyengar

    Indian Journal of Dermatology, Venereology and Leprology
    |February 23, 2017
    PubMed
    Summary
    This summary is machine-generated.

    Bullosis diabeticorum, a rare skin condition in diabetics, can present with either intraepidermal or subepidermal blisters. This study observed both types in two patients, challenging previous assumptions.

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    Area of Science:

    • Dermatology
    • Endocrinology
    • Pathology

    Background:

    • Bullosis diabeticorum is a rare blistering disorder affecting patients with diabetes mellitus.
    • Historically, it was consistently described as an intraepidermal bullous disorder.

    Observation:

    • This study examined two patients diagnosed with bullosis diabeticorum.
    • The incidence of bullosis diabeticorum was noted to be 1% in a cohort of 200 diabetic patients.

    Findings:

    • Contrary to previous reports, bullosis diabeticorum can manifest with subepidermal bullae.
    • One patient presented with an intraepidermal bulla, while the other exhibited a subepidermal bulla.

    Implications:

    • These findings suggest that bullosis diabeticorum is not exclusively an intraepidermal condition.
    • The varied presentation necessitates a broader understanding of its histopathological characteristics.
    • Further research is warranted to elucidate the factors influencing bulla formation in diabetic patients.