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Synthesis and characterization of potential tumor scintigraphic agents
A B Awaluddin1, J J Jacobs, D W Bourne
1Isotope Division, Prime Minister's Department, Bangi, Malaysia.
International Journal of Radiation Applications and Instrumentation. Part A, Applied Radiation and Isotopes
|January 1, 1987
Abstract:
Potential tumor imaging radiopharmaceutical agents have been prepared by attaching a cisplatin derivative to a ligand capable of forming a stable complex with 99mTc. Three new organometallic compounds, with iminodiacetic acid as the 99mTc chelating group and 2,3-diaminopropionamide as the platinum complexing group, have been prepared and characterized. Preliminary biodistribution studies in tumor bearing mice support the utility of this approach.