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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Brain Imaging01:14

Brain Imaging

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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
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Related Experiment Video

Updated: Mar 7, 2026

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
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Multiple-mouse Neuroanatomical Magnetic Resonance Imaging

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Studying neuroanatomy using MRI.

Jason P Lerch1,2, André J W van der Kouwe3,4, Armin Raznahan5

  • 1Program in Neuroscience and Mental Health, The Hospital for Sick Children, Toronto, Canada.

Nature Neuroscience
|February 24, 2017
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Summary
This summary is machine-generated.

Structural magnetic resonance imaging (MRI) offers valuable brain insights but requires careful interpretation due to indirect measurements and potential artifacts. Continued advancements promise deeper understanding of brain structure and function.

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Area of Science:

  • Neuroscience
  • Medical Imaging
  • Radiology

Background:

  • Neuroimaging, particularly magnetic resonance imaging (MRI), is crucial for understanding brain function, development, aging, and disease.
  • Advances in MRI acquisition, processing, and modeling have driven progress in neuroanatomy.
  • MRI provides indirect biological measurements, necessitating careful interpretation.

Purpose of the Study:

  • To review methods for measuring brain structure at macro- and mesoscopic levels.
  • To discuss techniques for inferring microstructural properties from MRI data.
  • To highlight key artifacts and confounds that can impact anatomical MRI interpretation.

Main Methods:

  • Overview of structural MRI techniques for macro- and mesoscopic analysis.
  • Description of methods for inferring microstructural properties.
  • Identification and explanation of common MRI artifacts and interpretation challenges.

Main Results:

  • Structural MRI enables the study of brain anatomy, function, and changes across the lifespan and in disease.
  • Potential artifacts and interpretation issues can lead to erroneous conclusions.
  • Despite limitations, structural MRI remains a powerful tool for neuroscience research.

Conclusions:

  • Structural MRI is a promising tool for advancing our understanding of brain function and structure.
  • Improvements in methodology and cautious interpretation are essential for maximizing MRI's utility.
  • Continued research in neuroimaging techniques will further enhance insights into the brain.