Associations Among Infant Iron Deficiency, Childhood Emotion and Attention Regulation, and Adolescent Problem

Patricia East1, Erin Delker1, Betsy Lozoff2

  • 1University of California, San Diego.

Child Development
|February 25, 2017
PubMed

Insights

Infant iron deficiency anemia (IDA) is linked to adolescent problem behaviors like risky sex and alcohol use. This occurs through impaired childhood emotion regulation and attention, affecting long-term adjustment.

Area of Science:

  • Developmental Psychology
  • Pediatric Health
  • Neuroscience

Background:

  • High rates of iron deficiency (28%) and iron-deficiency anemia (17%) were observed in Chilean infants born between 1991-1996.
  • This period predates national iron fortification programs, offering a unique study population.

Purpose of the Study:

  • To investigate if infant iron deficiency (ID) influences adolescent problem behaviors.
  • To determine if poor childhood regulatory abilities mediate the relationship between infant ID and adolescent outcomes.

Main Methods:

  • Longitudinal study of 1,116 Chilean infants from infancy through adolescence (ages 10 and 14).
  • Assessment of iron deficiency anemia (IDA) in infancy.
  • Evaluation of emotion regulation and attentional control in childhood.
  • Measurement of problem behaviors (alcohol use, risky sexual behavior, risk-taking) in adolescence.

Main Results:

  • Infant IDA was significantly associated with excessive alcohol use and risky sexual behavior in adolescence.
  • Poor emotion regulation in childhood was identified as a key mediator.
  • Attentional control deficits at age 10 linked infant IDA to adolescent risk-taking.

Conclusions:

  • Infant iron deficiency anemia can have lasting impacts on adolescent behavioral adjustment.
  • Childhood regulatory abilities play a crucial role in how infant IDA affects long-term outcomes.
  • Findings highlight the importance of early iron status for cognitive and emotional development.

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