Prostate cancer before renal transplantation: A multicentre study.
C Chahwan1, A Doerfler2, N Brichart3
1Urology and Transplantation department, CHU Côte-de-Nacre, Caen, France; Normandie Univ, France; UNICAEN, Caen, France.
Summary
Patients with prostate cancer (PC) treated before kidney transplantation (RT) had no recurrence. Radical prostatectomy is recommended for PC before RT to assess recurrence risk and potentially shorten RT waiting times.
Area of Science:
- Urology
- Oncology
- Nephrology
Background:
- Surgical considerations and oncological outcomes of renal transplantation (RT) following localized prostate cancer (PC) treatment remain unclear.
- This study investigates patients with a history of PC who underwent kidney transplantation.
Purpose of the Study:
- To evaluate the oncological outcomes and surgical aspects of renal transplantation in patients with a history of prostate cancer.
- To determine the safety and feasibility of RT after PC treatment.
Main Methods:
- Retrospective multicenter study including 52 patients diagnosed with PC before RT between December 1993 and December 2015.
- Analysis of PC treatment modalities (radical prostatectomy, radiotherapy) and RT surgical details (operative time, bleeding).
Main Results:
- Median age at PC diagnosis was 59.8 years, with most cases (51/52) classified as low or intermediate risk.
- Median time from PC treatment to RT was 35.7 months.
- No PC recurrence was observed after a median follow-up of 36 months.
Conclusions:
- Radical prostatectomy is advised for PC diagnosed before RT to accurately assess recurrence risk.
- For low-risk PC, a multidisciplinary approach may allow for a reduced waiting time before renal transplantation.
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