Related Experiment Video
Updated: Mar 7, 2026

06:53
Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
3.3K
Solitary Thumb Acrometastasis Identified on Bone Scintigraphy
1From the Department of Nuclear Medicine, The Third Hospital, Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Clinical Nuclear Medicine
|February 28, 2017
Summary
A lung adenocarcinoma metastasized to a patient's left thumb, initially detected via Tc-MDP bone scan. Pathological examination confirmed the metastasis in the first metacarpal bone.
Area of Science:
- Oncology
- Radiology
- Orthopedic Oncology
Background:
- Lung adenocarcinoma is a common malignancy.
- Metastasis to unusual sites can occur.
- Bone scans are used to detect osseous metastases.
Observation:
- A 45-year-old man with a history of lung adenocarcinoma presented for a bone scan.
- Intense tracer uptake was noted in the left thumb, atypical for metastases elsewhere.
- CT imaging revealed sclerotic changes and bone destruction in the left thumb.
Findings:
- Pathological examination of the resected left first metacarpal bone confirmed metastasis from lung adenocarcinoma.
- This case highlights an unusual site of metastasis.
Implications:
- Early detection of metastasis to uncommon sites is crucial for patient management.
- Multimodality imaging and pathological confirmation are essential for accurate diagnosis.
- Understanding rare metastatic patterns aids in comprehensive cancer care.

