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[Acute generalized exanthematous pustulosis induced by phloroglucinol]
N Brahimi1, E Maubec2, T Petit3
1Service de dermatologie, hôpital Bichat, université Denis-Diderot, Sorbonne Paris Cité, AP-HP, 46, rue Henri-Huchard, 75877 Paris cedex 18, France.
Annales De Dermatologie Et De Venereologie
|March 1, 2017
Summary
This study details the first reported case of acute generalized exanthematous pustulosis (AGEP), a severe drug reaction, triggered by phloroglucinol. The diagnosis was confirmed by drug reintroduction, leading to a favorable outcome after discontinuation.
Area of Science:
- Dermatology
- Pharmacovigilance
- Internal Medicine
Background:
- Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse drug reaction.
- Phloroglucinol, commonly used for smooth muscle spasms, has not been previously implicated in AGEP.
- This case highlights a novel association between phloroglucinol and AGEP.

