Cutaneous basidiobolomycosis: Seven cases in southern Benin
F Atadokpédé1, J Gnossikè1, H Adégbidi1
1Dermatology department, CNHU-HKM, faculté des sciences de la santé, BP 186, Cotonou, Benin.
Annales De Dermatologie Et De Venereologie
|March 1, 2017
Summary
Cutaneous basidiobolomycosis, a fungal infection, is uncommon in southern Benin, primarily affecting children. Diagnosis presents challenges due to non-specific symptoms and limited resources.
Area of Science:
- Mycology
- Infectious Diseases
- Dermatology
Background:
- Cutaneous basidiobolomycosis is the most common form of entomophthoramycosis.
- This study reports on seven cases diagnosed in Benin.
Purpose of the Study:
- To describe the clinical presentation, diagnosis, and treatment of cutaneous basidiobolomycosis in Benin.
- To highlight diagnostic challenges in a resource-limited setting.
Main Methods:
- A retrospective observational study was conducted from 2010 to 2015.
- Data were collected from the Buruli ulcer treatment centre in Pobè and the national teaching hospital in Cotonou.
Main Results:
- Seven cases of cutaneous basidiobolomycosis were diagnosed in children (mean age 9.53 years) from southeast Benin.
- Clinical presentation included hard, well-defined subcutaneous plaques with hyperpigmentation; laboratory findings revealed inflammatory anemia and hypereosinophilia.
- Histopathology showed granulomatous lesions with Splendore-Hoeppli phenomenon; Basidiobolus ranarum was identified in three cases. Patients treated with ketoconazole or itraconazole showed good outcomes.
Conclusions:
- Cutaneous basidiobolomycosis is uncommon in southern Benin, with diagnosis being challenging due to non-specific clinical signs and limited resources.
- The condition primarily affects children and requires prompt diagnosis and treatment.
Keywords:
Basidiobolomycose cutanéeBasidiobolus ranarumBeninBéninChildCutaneous basidiobolomycosisEnfantsMore Related Videos
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