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Updated: Mar 7, 2026

Intraoperative Ultrasound in Spinal Surgery
Published on: August 17, 2022
[Cervical paraspinal chordoma, a condition we should know. A case report]
Juan Mesa-Quesada1, Elisa Roldán-Romero1, Jesús A Lozano-Sánchez2
1Sección de Neurorradiología Diagnóstica y Terapéutica, UGC de Radiodiagnóstico, Hospital Universitario Reina Sofía, Córdoba, España.
This study reports an extremely rare case of a left para-spinal chordoma at the C2-C4 vertebral level in a young male. Histopathological analysis confirmed the diagnosis, highlighting the tumor
Area of Science:
- Neurosurgery
- Orthopedic Oncology
- Pathology
Background:
- Chordoma is a rare, slow-growing bone tumor originating from notochordal remnants.
- Typically found at the skull base or sacrococcygeal region, cervical chordomas are exceptionally rare, accounting for only 6% of cases.
- This case involves a para-spinal chordoma at the C2-C4 vertebral level, a location with fewer than 10 reported instances.
Observation:
- A young male presented with a left para-spinal tumor at the C2-C4 level.
- Radiographic imaging indicated a slow-growing, cystic tumor with bone erosion and encasement of the left vertebral artery.
- Surgical excision was performed for the observed tumor.
Findings:
- Histopathological examination of the surgical specimen revealed significant cell proliferation.
- The tumor exhibited a myxoid-chondroid stroma with epithelioid and physaliphorous (PAS+) cells.
- These cellular features are consistent with a diagnosis of chordoma.
Implications:
- This case expands the understanding of rare chordoma presentations in the cervical spine.
- Highlights the importance of considering chordoma in the differential diagnosis of spinal tumors, even in unusual locations.
- Further research into the management and treatment of rare chordoma variants is warranted.
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