Related Experiment Video
Updated: Mar 7, 2026
05:57
ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection
Published on: February 10, 2017
8.9K
Prophylactic stenting for esophageal stricture prevention after endoscopic submucosal dissection
1Ke-Da Shi, Feng Ji, Department of Gastroenterology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310000, Zhejiang Province, China.
World Journal of Gastroenterology
|March 2, 2017
Summary
Prophylactic esophageal stenting may reduce strictures after endoscopic submucosal dissection (ESD) for large lesions. Further research is needed to confirm efficacy and safety before widespread adoption.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
Background:
- Endoscopic submucosal dissection (ESD) offers a minimally invasive approach for superficial esophageal cancer.
- Large lesion ESD can lead to esophageal strictures, impacting patient quality of life.
- Stricture prevention is crucial for expanding endoscopic therapy options.
Discussion:
- Metallic self-expandable stents and biodegradable stents are being investigated for post-ESD stricture prevention.
- Limited studies suggest prophylactic stenting may decrease stricture rates and bougie dilation needs.
- Stent migration is a primary complication requiring further stent design innovation.
Key Insights:
- Prophylactic stenting shows promise in reducing esophageal strictures post-ESD.
- Current evidence is preliminary, lacking definitive practice standards.
- Randomized controlled trials are essential to validate efficacy and safety.
Outlook:
- Further research is needed to establish optimal stenting strategies for stricture prevention.
- Development of stents with lower migration rates and minimal tissue reaction is necessary.
- Long-term follow-up in randomized controlled trials will determine the viability of prophylactic stenting.
Keywords:
Biodegradable stentEndoscopic submucosal dissectionEsophageal strictureMetallic self-expandable stentStricture preventionMore Related Videos
Related Concept Videos
01:26Esophageal Strictures-II: Clinical Features and Management
804
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
804
01:30Esophageal Strictures-I: Introduction
1.0K
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
1.0K
01:21Barrett Esophagus-II: Clinical Manifestations and Management
1.3K
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
1.3K
01:29Endoscopic Procedures I: Esophagogastroduodenoscopy
1.7K
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
During an EGD, the endoscope can be used to:
1.7K
01:21Barrett Esophagus-I: Introduction
1.1K
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
1.1K
01:28Esophageal Perforation-II: Clinical Manifestations and Management
865
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Clinical Manifestations:
865