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Published on: March 11, 2022
Charcot Foot
H Zwipp1, S Rammelt1, C Dahlen1
1Klinik und Poliklinik für Unfall- und Wiederherstellungschirurgie, Universitätsklinikum Carl Gustav Carus, TU Dresden, Germany.
Insights
Charcot foot, a stage of hereditary motor and sensory neuropathy (HMSN), involves progressive muscle atrophy and severe foot/ankle deformities. Early detection and surgical interventions can prevent further complications and improve long-term outcomes.
Area of Science:
- Neurology
- Orthopedic Surgery
- Genetics
Background:
- Charcot foot is historically linked to stage 4 of hereditary motor and sensory neuropathy (HMSN), also known as Charcot-Marie-Tooth disease.
- This progressive neurological disorder primarily affects the feet and ankles, leading to muscle weakness, deformities like pes cavus, and eventual arthropathy.
- The condition can advance to stage 5, characterized by neuropathic fractures of the ankle due to repetitive microtrauma.
Purpose of the Study:
- To differentiate Charcot foot in HMSN from diabetic Charcot ankle.
- To outline diagnostic and therapeutic strategies for both conditions.
- To emphasize the importance of early detection and appropriate management to prevent severe deformities and functional loss.
Main Methods:
- Review of clinical presentations and historical definitions of Charcot foot.
- Discussion of diagnostic tools, including nerve conduction studies.
- Analysis of surgical interventions such as tendon transfers, osteotomies, arthrodesis, and amputation.
- Emphasis on post-operative care including non-weight-bearing and immobilization.
Main Results:
- Charcot foot in HMSN presents with intrinsic foot muscle weakness, progressing to fixed deformities and ankle arthrosis.
- Diabetic arthropathy (Type IV) requires specific management, often tibiocalcanear arthrodesis.
- Surgical interventions can correct deformities and prevent the need for more extensive procedures like triple arthrodesis.
- Appropriate post-operative care significantly reduces implant failure rates.
Conclusions:
- Early diagnosis of Charcot foot in HMSN through nerve conduction studies is crucial for timely intervention.
- Surgical correction, including ankle or double arthrodesis, is indicated for advanced stages of Charcot foot and diabetic arthropathy.
- Prolonged non-weight-bearing and immobilization are essential for successful surgical outcomes in both conditions.
- Salvage procedures like modified Pirogoff amputation may be necessary for infection or necrosis.
Abstract:
Charcot foot in its original sense is equivalent to stage 4 of hereditary motor and sensory neuropathy (HMSN) which is known as Charcot-Marie-Tooth disease since 1886. This entity, which can be subdivided into 3 groups including subgroups, predominantly begins during childhood and progresses slowly. The first symptom, often unnoticed by the patient for a long period, is weakness of the intrinsic foot muscles with consecutive hammer-toe formation and mobile pes cavus. Progredient atrophy of the peroneal, extensor, tibialis posterior and finally triceps surae muscles leads to fixed pes cavus varus excavatus with severe varus deformity of the hindfoot, secondary varus position of the talus at the ankle level and subsequent arthrosis of the medial compartment. Permanent varus deformity of the ankle almost invariably leads to stress fractures of the malleoli because of repetitive microtrauma (stage 5 of HMSN).Early detection of the disease with nerve conduction studies at clinical suspicion allows tibialis posterior transfer, correctional osteotomy of the hindfoot or arthrodesis of Chopart's or Lisfranc's joint and can postpone or prevent the otherwise inevitable triple arthrodesis which has a less favorable long-term prognosis. At stage 4 (manifest Charcot foot) and stage 5 (neuropathic fracture of the ankle) a reorientating ankle arthrodesis is advocated, with additional subtalar pathology correctional double arthrodesis becomes necessary.In diabetic arthropathy of the ankle (Type IV according to Sanders and Frykberg), which is often referred to as "Charcot Ankle", tibiocalcanear arthrodesis is indicated. In case of supervening infection or extensive necrosis a modified Pirogoff amputation is carried out as a salvage procedure.Doubled periods of non weight-bearing, immobilization and brace protection of the ankle help to reduce the frequently observed implant failure in both forms of osteoarthropathy. In addition to stable implants retrograde calcaneotalotibial transfixation with a Steinmann pin may help to protect the achieved result despite prolonged bone consolidation.
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