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[Metabolic syndrome as a cause of reduced ejaculate fertility in patients with prostatic tuberculosis]
A V Osadchii1,2, E V Kulchavenya1,2
1Novosibirsk Tuberculosis Research Institute of Minzdrav of Russia.
Introduction:
Metabolic syndrome (MS) negatively affects the quality of ejaculate, especially in patients with chronic prostatitis.
Material And Methods:
To determine the effect of metabolic syndrome on semen parameters in patients with tuberculosis of the prostate (TP), a study of 72 patients with prostatic tuberculosis was conducted. MS was diagnosed when at least three of the five following medical conditions were found: central obesity, elevated levels of plasma triglycerides, high blood pressure, hyperglycemia and decreased levels of high-density lipoproteins. Semen parameters were compared in patients with tuberculosis of the prostate with and without MS.
Results:
41% of patients with prostatic tuberculosis had metabolic syndrome, which was associated with a 1.5, 1.4 and 2.5 fold decreases in the number of sperm, sperm concentration, and the number of normal sperm forms, respectively.
Conclusions:
These findings provide the rationale for developing specific therapies aimed at restoring ejaculate fertility in patients with prostatic tuberculosis, considering that almost a half of them have MS.
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