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Published on: November 11, 2014
Continuous Intravenous Milrinone Therapy in Pediatric Outpatients
Michelle Curley1, Jill Liebers, Roy Maynard
1Pediatric Home Service (Ms Curley and Dr Liebers), and Children's Hospitals and Clinics of Minnesota (Dr Maynard). Michelle Curley, RN, CRNI®, is an infusion nurse manager at Pediatric Home Service, Roseville, MN. Jill Liebers, PharmD, is a pharmacy manager at Pediatric Home Service, Roseville, MN. Roy Maynard, MD, is a practicing pediatric pulmonologist on staff at Children's Hospitals and Clinics of Minnesota, Minneapolis, MN. He is also the medical director at Pediatric Home Service, Roseville, MN.
Abstract:
Milrinone is a phosphodiesterase 3 inhibitor with both positive inotropic and vasodilator properties. Administered as a continuous infusion, milrinone is indicated for the short-term treatment of patients with acute decompensated heart failure. Despite limited data supporting long-term milrinone therapy in adults with congestive heart failure, children managed as outpatients may benefit from continuous milrinone as a treatment for cardiac dysfunction, as a destination therapy for cardiac transplant, or as palliative therapy for cardiomyopathy. The aim of this article is to review the medical literature and describe a home infusion company's experience with pediatric outpatient milrinone therapy.
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