Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dome-shaped macula in high myopia: Prevalence and clinical characteristics in a French cohort.

Acta ophthalmologica·2026
Same author

Estimation of high myopia-associated optic neuropathies: the Two-Continent Eye Study.

The British journal of ophthalmology·2026
Same author

Intereye differences in myopic macular degeneration, intraocular pressure and axial length: the Two-Continent Eye Study.

The British journal of ophthalmology·2026
Same author

Subretinal drusenoid deposits (reticular pseudodrusen) in the general population: a European multicohort study.

The British journal of ophthalmology·2026
Same author

Genome-wide discovery reveals 30 loci for choroidal thickness and uncovers potential causal links with angle-closure glaucoma.

medRxiv : the preprint server for health sciences·2026
Same author

Prevalence and associations of intraretinal hyperreflective foci in age-related macular degeneration: the Beijing Eye Study.

The British journal of ophthalmology·2026

Related Experiment Video

Updated: Mar 6, 2026

3D Visualization of Retinal Vascular Pericytes in Mice by Immunostaining
09:22

3D Visualization of Retinal Vascular Pericytes in Mice by Immunostaining

Published on: November 1, 2024

1.4K

Peripapillary choroidal vascular layers: the Beijing Eye Study.

Jie Xu1, Ya Xing Wang1, Ran Jiang1

  • 1Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Lab, Beijing, China.

Acta Ophthalmologica
|March 3, 2017
PubMed
Summary

The peripapillary choroidal layers, including the small-to-medium vessel layer (SMVL) and large vessel layer (LVL), are thickest superiorly. Both layers increase with younger age and higher cognitive function, with LVL decreasing more than SMVL in older individuals.

Keywords:
Haller's layerSattler's layerchoroidepidemiologyperipapillary choroid

More Related Videos

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

4.3K
Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

428

Related Experiment Videos

Last Updated: Mar 6, 2026

3D Visualization of Retinal Vascular Pericytes in Mice by Immunostaining
09:22

3D Visualization of Retinal Vascular Pericytes in Mice by Immunostaining

Published on: November 1, 2024

1.4K
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

4.3K
Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

428

Area of Science:

  • Ophthalmology
  • Choroidal Imaging
  • Vascular Biology

Background:

  • The peripapillary choroid's vascular layers are crucial for optic nerve health.
  • Understanding their thickness and associations is vital for diagnosing and managing eye conditions.

Purpose of the Study:

  • To assess the thickness of the peripapillary choroidal layers, specifically the large vessel layer (LVL) and small-to-medium vessel layer (SMVL).
  • To investigate associations between these peripapillary choroidal layers and various demographic, ocular, and cognitive factors.

Main Methods:

  • Utilized spectral-domain optical coherence tomography (SD-OCT) in the population-based Beijing Eye Study (n=3000, age 50+).
  • Measured LVL and SMVL thickness in a circular scan around the optic nerve head.
  • Calculated the SMVL-to-LVL thickness ratio and analyzed associations with age, cognitive function, axial length, and other parameters.

Main Results:

  • Peripapillary SMVL and LVL were thickest superiorly and thinnest inferiorly.
  • Thicker SMVL and LVL were associated with younger age, higher cognitive function, and shorter axial length.
  • A higher SMVL-to-LVL ratio correlated with older age, longer axial length, and larger optic disc area.

Conclusions:

  • Peripapillary choroidal layer thickness varies by location and is associated with age and cognitive function.
  • LVL thickness decreases more than SMVL thickness with increasing age and axial length.
  • The link between peripapillary choroidal thickness and cognitive function warrants further investigation.