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Updated: Mar 6, 2026

Microfluidic Mixers for Studying Protein Folding
Published on: April 10, 2012
Rapid mixing with high-throughput in a semi-active semi-passive micromixer
Golak Kunti1, Anandaroop Bhattacharya1, Suman Chakraborty1
1Department of Mechanical Engineering, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India.
Abstract:
In this paper, we investigate a novel alternating current electrothermal (ACET) micromixer driven by a high efficiency ACET micropump. The micromixer consists of thin film asymmetric pairs of electrodes on the microgrooved channel floor and array of electrode pairs fabricated on the top wall. By connecting electrodes with AC voltage, ACET forces are induced. Asymmetric microgrooved electrodes force the fluids along the channel, while lateral vortex pairs are generated by symmetric electrode pairs located on the top wall. Waviness of the floor increases contact area between two confluent streams within a narrow confinement. An active mixer operates as a semi active semi passive mixer. Effects of various parameters are investigated in details in order to arrive at an optimal configuration that provides for efficient mixing as well as appreciable transport. It is found that using a specific design, uniform and homogeneous mixing quality with mixing efficiency of 97.25% and flow rate of 1.794μm2/ min per unit width of the channel can be achieved.
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