Related Experiment Video
Updated: Mar 6, 2026

Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance
Published on: March 7, 2025
Peptic Ulcer Disease in Bangladesh: A Multi-centre Study
1Dr Chanchal Kumar Ghosh, Associate Professor, Department of Gastroenterology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbagh, Dhaka, Bangladesh;
Peptic ulcer prevalence in Bangladesh has decreased significantly since the 1980s. Endoscopic data from 2012-2013 reveals lower rates of peptic ulcer disease (PUD) and related complications.
Area of Science:
- Gastroenterology
- Epidemiology
Background:
- Global incidence of peptic ulcer disease (PUD) shows a declining trend.
- Previous studies indicated a PUD point prevalence of approximately 15% in Bangladesh during the 1980s.
Purpose of the Study:
- To determine the current prevalence of peptic ulcer disease (PUD) through endoscopic examinations in Bangladesh.
- To identify any shifts in the occurrence trends of PUD within Bangladesh.
Main Methods:
- Retrospective analysis of endoscopic records from tertiary referral centers in Dhaka city.
- Data collected between January 2012 and July 2013.
- Inclusion criteria: patients diagnosed with duodenal ulcer, benign gastric ulcer, pre-pyloric ulcer, or gastric outlet obstruction due to peptic ulcer.
Main Results:
- A total of 5608 subjects were analyzed.
- Duodenal ulcers were diagnosed in 415 patients (7.4%).
- Benign gastric ulcers were found in 184 patients (3.28%).
- Gastric outlet obstruction related to peptic ulcer affected 23 patients (0.40%).
Conclusions:
- The current endoscopic prevalence of peptic ulcer disease (PUD) in Bangladesh is lower than previously reported.
- These findings suggest a continued downward trend in PUD incidence in the region.
More Related Videos
Related Concept Videos
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Peptic Ulcer Disease IV: Management
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors
Drugs for Peptic Ulcer Disease: Prostaglandin Analogs as Mucosal Protective Agents
Non-steroidal anti-inflammatory drugs (NSAIDs) can induce peptic ulcers by inhibiting cyclooxygenase, decreasing...
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy

