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Updated: Mar 6, 2026

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats
Published on: May 27, 2021
[Tic suppression is a new evidence-based non-farmacological treatment of chronic tic disorder]
Camilla Birgitte Sørensen1, Nanette Mol Debes, Liselotte Skov
1camilla.birgitte.soerensen@gmail.com.
Abstract:
Chronic tic disorder and Tourette syndrome are both chronic and impairing neurobiological disorders starting in childhood with a prevalence between 0.4 and 1.6%. Traditionally, pharmacological therapies have been first-line treatment but are often associated with adverse effects. Recently behavioural therapy has shown to be effective in treating tics and today both habit reversal (HR) and exposure and response prevention (ERP) are recommended as first-line treatments. HR and ERP are now available for Danish patients. This article describes the evidence and recommendations for both therapies.
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