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Updated: Mar 6, 2026
High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
Published on: December 16, 2022
Abnormal 18F-FDG and 82Rb PET Findings in Chagas Heart Disease
Medhi S Salimy1, Purvi J Parwani, Kanae Mukai
1From the *Section of Nuclear Medicine, Department of Radiology and Biomedical Imaging, and †Department of Cardiology, University of California, San Francisco, San Francisco, CA.
Abstract:
Uptake of the radiopharmaceutical F-FDG visualized by PET imaging can reflect abnormal myocardial inflammation. When utilized in conjunction with other imaging modalities, such as echocardiography, PET F-FDG imaging can help distinguish between active cardiac sarcoidosis and other etiologies of nonischemic cardiomyopathy. We present a case of a 46-year-old man with nonischemic cardiomyopathy and ventricular tachycardia who underwent an echocardiogram suggestive of cardiac Chagas disease. A subsequent F-FDG PET demonstrated abnormal hypermetabolism. The diagnosis was confirmed by positive serologic examination results.
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