Diastolic dysfunction in hypertension.
R Nazário Leão1, P Marques da Silva2
1Unidade Funcional Medicina 2, Hospital São José, Centro Hospitalar Lisboa Central - EPE, Lisboa, Portugal; Nova Medical School, Lisboa, Portugal.
Hipertension Y Riesgo Vascular
|March 8, 2017
Summary
Hypertension can lead to asymptomatic left ventricular diastolic dysfunction, a precursor to heart failure. Early diagnosis and treatment are crucial for managing this condition in hypertensive patients.
Area of Science:
- Cardiology
- Hypertension Research
- Heart Failure Studies
Background:
- Hypertension and coronary heart disease are leading risk factors for heart failure.
- Hypertensive heart disease progresses through myocardial fibrosis and altered left ventricular geometry, often asymptomatically.
- Left ventricular diastolic dysfunction (LVDD) is a key, underappreciated component of this continuum.
Purpose of the Study:
- To review the epidemiology of LVDD in hypertensive patients.
- To discuss the latest advancements in understanding LVDD pathophysiology.
- To cover current diagnostic and therapeutic strategies for LVDD.
Main Methods:
- Literature review of epidemiological data.
- Synthesis of recent research on LVDD pathophysiology.
- Analysis of diagnostic tools and treatment options for LVDD.
Main Results:
- LVDD is highly prevalent in hypertensive individuals.
- LVDD precedes overt heart failure symptoms and is linked to higher cardiovascular risk.
- Understanding LVDD is critical for clinical practice, though it remains poorly understood.
Conclusions:
- LVDD is a significant clinical entity in hypertensive patients, associated with adverse outcomes.
- Further research into pathophysiology, diagnosis, and treatment is warranted.
- This review provides a comprehensive overview for clinicians and researchers.
Keywords:
Diastolic dysfunctionDisfunción diastólicaEnfermedad cardíaca hipertensivaGeometría ventricular izquierdaHeart failure with preserved ejection fractionHipertensiónHypertensionHypertensive heart diseaseInsuficiencia cardíaca con fracción de eyección preservadaLeft Ventricular geometryMore Related Videos
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