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In vitro selection of random peptides against artificial lipid bilayers: a potential tool to immobilize molecules on

Shota Kobayashi1, Takuya Terai, Yuki Yoshikawa

  • 1Graduate School of Science and Engineering, Saitama University, 255 Shimo-Okubo, Sakura-ku, Saitama City, Saitama 338-8570, Japan. nemoto@fms.saitama-u.ac.jp.

Chemical Communications (Cambridge, England)
|March 9, 2017
PubMed

The first in vitro selection of binding peptides against artificial lipid membranes from a random peptide library using an in vitro display method (cDNA display) is reported. The selected peptide, LB-1, has both amphiphilic and cationic regions, and proteins fused to LB-1 can be immobilized on the liposome surface.

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