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Related Experiment Videos

C S Betz1,2, A Leunig3

  • 1Klinik für Hals-, Nasen- und Ohrenheilkunde der Ludwig-Maximilians-Universität, Klinikum Großhadern, München. cbetz@life.med.uni-muenchen.de.

HNO
|March 9, 2017
PubMed
Summary
This summary is machine-generated.

Fluorescence diagnostics improve tumor visualization in ENT oncology by exciting fluorescent markers. This review covers methods, biophysical basics, and current systems for upper aerodigestive tract cancer diagnosis.

Keywords:
AutofluorescenceFluorescence diagnosisHead and neck cancerReview

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Area of Science:

  • Oncology
  • Medical Imaging
  • Biophysics

Context:

  • Malignant tumors in the upper aerodigestive tract present diagnostic challenges.
  • Optical measurement of fluorescence signals aids in tumor visualization.

Purpose:

  • To provide ENT specialists with a comprehensive understanding of fluorescence diagnostic methods.
  • To review the current research status and commercially available systems for fluorescence diagnosis in ENT oncology.

Summary:

  • Fluorescence diagnostics utilize specific excitation of endogenous or exogenous tumor-selective fluorescent markers for enhanced tumor visualization.
  • The review details the historical synopsis, biophysical principles, and clinical difficulties associated with fluorescence diagnosis.
  • A critical evaluation of current research and commercial systems in ENT oncology is presented.

Impact:

  • Enhances diagnostic accuracy for upper aerodigestive tract cancers.
  • Informs ENT specialists about the latest advancements and applications of fluorescence diagnostics.
  • Provides insights into future directions for fluorescence-guided tumor detection.