Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

13.5K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
13.5K
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

683
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
683
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

845
Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
845
Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

13.5K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
13.5K
Olfaction01:25

Olfaction

49.3K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
49.3K
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

564
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
564

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>In Vivo</i> confocal microscopy evaluation of corneal layer alterations in patients with trigeminal neuralgia.

Cephalalgia : an international journal of headache·2026
Same author

Melatonin and oxidative DNA damage in REM- and NREM-related obstructive sleep apnea: an exploratory analysis of sleep-stage phenotypes.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·2026
Same author

Transcranial doppler-derived cerebrovascular resistance changes during vagus nerve stimulation in drug-resistant epilepsy.

Epilepsy research·2026
Same author

Alpha and Beta Powers in EEG: How Audio-Visual Stimulation Influences Anxiety.

Applied psychophysiology and biofeedback·2025
Same author

Assessment of interoceptive accuracy in individuals with epilepsy.

Epilepsy & behavior : E&B·2025
Same author

Evaluation of cortical excitability with transcranial magnetic stimulation in patients with obstructive sleep apnea syndrome.

Neurophysiologie clinique = Clinical neurophysiology·2025

Related Experiment Video

Updated: Mar 6, 2026

Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols
15:04

Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols

Published on: May 20, 2016

11.5K

Does positive airway pressure therapy improve olfactory function?

Sabri Koseoğlu1, Serhan Derin1, Mustafa Yilmaz2

  • 1Department of Otolaryngology, Mugla Sitki Kocman University, Mugla, Turkey.

International Forum of Allergy & Rhinology
|March 9, 2017
PubMed
Summary
This summary is machine-generated.

Positive airway pressure (PAP) therapy significantly improved olfactory function in patients with obstructive sleep apnea syndrome (OSAS). This study highlights PAP therapy

Keywords:
nasal continuous positive airway pressureobstructive sleep apneaolfaction disordersolfactory nerve diseasepolysomnography

More Related Videos

Author Spotlight: Exploring Olfactory Influences on Corticospinal Excitability - Insights and Innovations in Neurological Research
06:13

Author Spotlight: Exploring Olfactory Influences on Corticospinal Excitability - Insights and Innovations in Neurological Research

Published on: January 19, 2024

1.6K
A Free-breathing fMRI Method to Study Human Olfactory Function
10:42

A Free-breathing fMRI Method to Study Human Olfactory Function

Published on: July 30, 2017

10.2K

Related Experiment Videos

Last Updated: Mar 6, 2026

Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols
15:04

Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols

Published on: May 20, 2016

11.5K
Author Spotlight: Exploring Olfactory Influences on Corticospinal Excitability - Insights and Innovations in Neurological Research
06:13

Author Spotlight: Exploring Olfactory Influences on Corticospinal Excitability - Insights and Innovations in Neurological Research

Published on: January 19, 2024

1.6K
A Free-breathing fMRI Method to Study Human Olfactory Function
10:42

A Free-breathing fMRI Method to Study Human Olfactory Function

Published on: July 30, 2017

10.2K

Area of Science:

  • Otolaryngology
  • Sleep Medicine
  • Neuroscience

Background:

  • Severe obstructive sleep apnea syndrome (OSAS) is associated with olfactory dysfunction.
  • The impact of positive airway pressure (PAP) therapy on olfactory function in OSAS patients remains uninvestigated.

Purpose of the Study:

  • To investigate the effect of PAP therapy on olfactory impairment in patients diagnosed with OSAS.

Main Methods:

  • Thirty OSAS patients scheduled for PAP therapy were enrolled.
  • Participants underwent otorhinolaryngological examination and polysomnography.
  • Olfactory function was assessed using the "Sniffin' Sticks" test before and after 3 months of PAP therapy.

Main Results:

  • PAP therapy significantly reduced the apnea-hypopnea index (AHI) from 57.6 ± 29.8/hour to 9.5 ± 7.9/hour.
  • Significant improvements were observed in odor threshold (OT), odor discrimination (OD), odor identification (OI), and total TDI scores (p < 0.001 for all).
  • Mean total TDI scores increased from 28.48 ± 4.71 pre-treatment to 32.50 ± 3.88 post-treatment.

Conclusions:

  • Olfactory dysfunction is evident in patients with OSAS.
  • PAP therapy leads to significant improvements in olfactory function for OSAS patients.
  • Further research is warranted to elucidate the mechanisms underlying olfactory dysfunction in OSAS and the benefits of PAP therapy.