Related Experiment Video
Updated: Mar 6, 2026

Establishment of a Rat Model of Superior Sagittal-Sinus Occlusion via a Thread-Embolism Method
Published on: July 4, 2021
Dangerous Headache: A Case of Dural Venous Sinus Thrombosis with Protein S Deficiency
M Hari Kumar1, D Angeline Deepthi2, Deepak Ningombam Singh3
1Senior Lecturer, Department of Oral Medicine and Radiology, Saveetha Dental College & Hospital, Saveetha University , Chennai, Tamil Nadu, India .
Abstract:
Dural Venous Sinus Thrombosis (DVST) is a sporadic cause of headache. DVST is a recherché complication of maxillary sinus infection. Maxillary sinusitis infection may spread directly to orbit via lamina papyracea and it is expedited by the presence veins of breschet. The authors present a clinical case of dural sinus thrombosis with protein S deficiency and also describe an effective management approach for DVST.
Insights
Dural venous sinus thrombosis (DVST), a rare headache cause, can stem from maxillary sinusitis. This case highlights DVST management in a patient with protein S deficiency.
Area of Science:
- Neurology
- Vascular Medicine
- Infectious Disease
Background:
- Dural Venous Sinus Thrombosis (DVST) is an uncommon cause of headaches.
- Maxillary sinusitis is a rare but documented predisposing factor for DVST.
- Orbital complications can arise from sinusitis via venous connections.
Observation:
- A clinical case of DVST is presented.
- The patient exhibited protein S deficiency, a thrombophilia.
- Maxillary sinusitis was identified as a potential initiating factor.
Findings:
- The study details the presentation and diagnosis of DVST.
- Protein S deficiency was confirmed as a comorbidity.
- An effective management strategy for this specific DVST case was outlined.
Implications:
- This case underscores the importance of considering DVST in patients with sinusitis and headache.
- Identifying underlying thrombophilias like protein S deficiency is crucial for management.
- Effective DVST management protocols can improve patient outcomes.
Related Concept Videos
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Venous Thrombosis I: Introduction
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis IV: Nursing Management
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Nephrotic Syndrome I : Introduction

