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BDNF controls object recognition memory reconsolidation
Andressa Radiske1, Janine I Rossato1, Maria Carolina Gonzalez1
1Memory Research Laboratory, Brain Institute, Federal University of Rio Grande do Norte, Av. Nascimento de Castro 2155, RN 59056-450 Natal, Brazil.
Neurobiology of Learning and Memory
|March 10, 2017
Abstract:
Reconsolidation restabilizes memory after reactivation. Previously, we reported that the hippocampus is engaged in object recognition memory reconsolidation to allow incorporation of new information into the original engram. Here we show that BDNF is sufficient for this process, and that blockade of BDNF function in dorsal CA1 impairs updating of the reactivated recognition memory trace.
