Cohort description: The Danish study of Functional Disorders

Area of Science:

• Epidemiology
• Psychiatry
• General Medicine

Background:

• Functional somatic syndromes (FSS) are common and poorly understood conditions.
• Existing medical explanations for FSS are limited, and their definition remains debated.
• The Danish study of Functional Disorders (DanFunD) cohort was established to address these knowledge gaps.

Purpose of the Study:

• To estimate the prevalence and incidence of FSS in the general population.
• To identify risk factors and pathogenic pathways associated with FSS.
• To explore the consequences of FSS on health, lifestyle, and healthcare utilization.

Main Methods:

• A large, population-based cohort of 9,656 individuals aged 18-76 years.
• Utilized screening questionnaires for five FSS types and bodily distress syndrome.
• Included diagnostic interviews, physical examinations, health questionnaires, and biobanking.

Main Results:

• Established a comprehensive dataset on FSS epidemiology and related factors.
• Collected extensive data on physical and mental health, lifestyle, and social determinants.
• Created a biobank and linked registry data for long-term follow-up.

Conclusions:

• The DanFunD cohort provides a robust foundation for future research on FSS.
• Findings will enhance understanding of FSS etiology, impact, and clinical management.
• Ongoing projects will yield significant insights into these prevalent conditions.